The usual Descovy dosage for HIV treatment and HIV prevention (PrEP) is one tablet per day. Specific dosages may vary depending on your body weight. It’s important to take the Descovy dosage your doctor prescribes.
Descovy (emtricitabine/tenofovir alafenamide) is used in adults and some children for:
- HIV treatment
- HIV preexposure prophylaxis (PrEP)
Descovy contains the active ingredients emtricitabine and tenofovir alafenamide. Both are nucleoside reverse transcriptase inhibitors. (An active ingredient is what makes a drug work.)
This article describes the dosages of Descovy, as well as its strengths and how to take it. To learn more about Descovy, including details about its side effects and uses, see this in-depth Descovy article.
The information below describes dosages that are commonly used or recommended. But be sure to take the dosage your doctor prescribes for you. They’ll determine the best dosage to fit your needs.
The following table highlights the basics of Descovy’s dosage for HIV treatment and PrEP.
Dosages are in milligrams (mg), with the dosage of emtricitabine first and tenofovir alafenamide second (emtricitabine/tenofovir alafenamide). Body weight is listed in kilograms (kg). One kilogram is approximately 2.2 pounds (lb).
| Age group and body weight | Once-daily Descovy dose for HIV treatment | Once-daily Descovy dose for PrEP |
|---|---|---|
| adults | 200 mg/25 mg | 200 mg/25 mg |
| adolescents* | 200 mg/25 mg | 200 mg/25 mg |
| children who weigh 25 kg or more | 200 mg/25 mg | — |
| children who weigh 14 kg to less than 25 kg | 120 mg/15 mg | — |
Note: Be sure to read for more details about Descovy’s recommended dosages for adults and children.
* For HIV treatment, adolescents follow the same dosing guidelines as other children. For PrEP, adolescents must weigh at least 35 kg.
Descovy’s form
Descovy comes as a tablet that you swallow.
Descovy’s strengths
Descovy comes in two strengths:
- 200 mg emtricitabine/25 mg tenofovir alafenamide (200 mg/25 mg)
- 120 mg emtricitabine/15 mg tenofovir alafenamide (120 mg/15 mg)
When used to treat HIV in adults, the daily dosage of Descovy is one 200-mg/25-mg tablet.
For treating HIV, Descovy is taken with other antiretroviral HIV drugs.
Most people who take Descovy for HIV PrEP will take one 200-mg/25-mg tablet per day.
A lower dose is recommended for some children. For details, see “Descovy dosage for children and adolescents.”
When used for PrEP in adults, the daily dosage of Descovy is one 200-mg/25-mg tablet.
Descovy can be prescribed for HIV treatment and PrEP in certain children and adolescents. See below for details.
Dosage for HIV treatment
The dosage of Descovy for children depends on their body weight.
For adolescents and children who weigh at least 25 kg, doctors prescribe one 200-mg/25-mg tablet per day. For children who weigh at least 14 kg but less than 25 kg, doctors prescribe one 120-mg/15-mg tablet per day.
For treating HIV, Descovy is taken with other antiretroviral HIV drugs.
Descovy isn’t approved for use in children who:
- weigh 14 kg to less than 35 kg and are taking a certain combination of antiretroviral HIV drugs
- weigh less than 14 kg
If you have questions about your child’s dosage for HIV treatment, talk with their doctor.
Dosage for PrEP
Descovy can be used for PrEP in adolescents who weigh at least 35 kg. The daily dosage is one 200-mg/25-mg tablet.
You’ll take Descovy once per day, with or without food. If you have trouble swallowing tablets, consider these tips for taking pills.
Note: If you’re taking Descovy for PrEP, you’ll take your tablet every day, not just when you think you’ve been exposed to HIV. If you have questions about the Descovy for PrEP routine, talk with your doctor or pharmacist.
Accessible drug containers and labels
Some pharmacies provide medication labels that:
- have large print or use braille
- feature a code you can scan with a smartphone to change the text to audio
Your doctor or pharmacist may be able to recommend pharmacies that offer these accessibility features if your current pharmacy doesn’t.
If you have trouble opening medication bottles, let your pharmacist know. They may be able to supply Descovy in an easy-open container. They may also have tips to help make it simpler to open the drug’s container.
Is Descovy used long term?
Yes, Descovy is usually used long term for HIV treatment and PrEP. If you and your doctor determine that it’s safe and effective for your condition, you’ll likely take it long term.
Below are answers to some commonly asked questions about Descovy’s dosage.
How does the dosage of Descovy compare with the dosage of Truvada?
The dosages of Descovy and Truvada both depend on body weight. Each drug comes as a tablet you take once per day. Descovy comes in two strengths, and Truvada comes in four strengths.
Descovy and Truvada both contain the active ingredient emtricitabine. They also contain second active ingredients that differ.
Adults and children who weigh more than 35 kg (about 77 lb) will usually take 200 mg of emtricitabine in Truvada or Descovy. For people who weigh less than 35 kg, the recommended dosages of emtricitabine differ between the two drugs.
If you have more questions about how the dosages of Descovy and Truvada compare, talk with your doctor. You can also read more about Truvada’s dosage.
Does Descovy require dosage adjustments in older adults?
Older adults (ages 65 years and older) usually don’t require dosage adjustments for Descovy. In studies of Descovy in older adults, someone’s age didn’t affect whether the drug was safe for them.
If you’re concerned about your dosage of Descovy, talk with your doctor.
How do you take Descovy for postexposure prophylaxis (PEP)?
Descovy’s manufacturer doesn’t provide a dosage for PEP because Descovy isn’t approved for this use. PEP is a combination of antiretroviral HIV medications taken after a potential exposure to HIV to help prevent transmission of the virus.
PEP isn’t the same as or a substitute for PrEP (Descovy’s approved use, along with HIV treatment). PEP is a short-term treatment in emergency situations, while PrEP (such as Descovy) is taken long term.
If you’re interested in PEP, talk with your doctor or pharmacist about options that may work for your situation.
If you miss a dose of Descovy, take it as soon as you remember. But if it’s almost time to take your next dose, skip the missed dose and take your next dose at its scheduled time. Talk with your doctor or pharmacist if you’re unsure when to take your next dose.
It’s important to take Descovy every day for the treatment to work. If you’re taking Descovy for PrEP, missing doses increases the risk of acquiring HIV. If you’re taking Descovy for HIV treatment, missing doses can cause the virus to develop drug resistance. With resistance, the drug no longer works on the virus.
If you need help remembering to take your dose of Descovy on time, try using a medication reminder. This can include setting an alarm or downloading a reminder app on your phone.
Do not take more Descovy than your doctor prescribes, as this can lead to serious side effects.
What to do in case you take too much Descovy
Call your doctor right away if you think you’ve taken too much Descovy. You can also call 800-222-1222 to reach to reach America’s Poison Centers or use its online resource. But if you have severe symptoms, immediately call 911 (or your local emergency number) or go to the nearest emergency room.
Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.
