Mydayis Interactions: Alcohol, Medications, and Others

Does Mydayis interact with other drugs?

Before you start taking Mydayis, tell your doctor and pharmacist about any prescription, over-the-counter, or other drugs you take. Sharing this information with them may help prevent possible interactions.

The following table lists drugs that may interact with Mydayis. Keep in mind that this table does not include all drugs that may interact with Mydayis. For more information about some of these interactions, see the “Drug interactions explained” section.

If you have questions about drug interactions that may affect you, talk with your doctor or pharmacist.

To learn whether Mydayis interacts with herbs, vitamins, or supplements, see the “Are there other interactions with Mydayis?” section.

When should I avoid Mydayis?

Certain health conditions or other factors could raise your risk of harm if you take Mydayis. In such cases, your doctor may not prescribe Mydayis for you. These are known as contraindications. Mydayis has contraindications, as described here:

If you take an MAOI drug: Your doctor likely will not prescribe Mydayis if you take a type of drug called a monoamine oxidase inhibitor (MAOI). They also likely will not prescribe Mydayis if you’ve taken an MAOI in the past 14 days. Taking Mydayis with or soon after an MAOI could cause a dangerous increase in blood pressure.

Examples of MAOIs include:

• isocarboxazid (Marplan)
• phenelzine (Nardil)
• tranylcypromine (Parnate)
• selegiline (Emsam, Zelapar)

If you take an MAOI, talk with your doctor about other treatments that may be better options for you.

If you’ve had an allergic reaction: If you’ve ever had an allergic reaction to Mydayis, any of its ingredients, or other amphetamines, your doctor likely will not prescribe Mydayis for you. This is because taking the drug could cause another allergic reaction. You can ask your doctor about other treatments that may be better options for you.

Before you start taking Mydayis, talk with your doctor if any of the factors mentioned here apply to you. Your doctor can determine whether Mydayis is safe for you to take.

Does Mydayis interact with alcohol?

You should avoid drinking alcohol with Mydayis. Mydayis comes as an extended-release capsule that releases the medication into your body slowly over several hours. Drinking alcohol with Mydayis can cause the medication to be released from the capsule more quickly. As a result, your body may absorb the medication faster, which can raise your risk of side effects from Mydayis. These side effects include anxiety and agitation.

If you have questions about consuming alcohol while taking Mydayis, talk with your doctor or pharmacist.

Drug interactions explained

Learn more about certain drug interactions that can occur with Mydayis.

Interaction with certain antidepressants

Mydayis can interact with certain antidepressants, which are used to treat depression and anxiety disorders.

Mydayis and certain antidepressants both can cause serotonin syndrome. This is a serious condition caused by high levels of serotonin in your body. So taking these drugs together can raise your risk of this side effect.

Some antidepressants that may interact with Mydayis are:

• tricyclic antidepressants, such as amitriptyline, clomipramine (Anafranil), and imipramine
• selective serotonin reuptake inhibitors, such as citalopram (Celexa), paroxetine (Paxil), and sertraline (Zoloft)
• serotonin-norepinephrine reuptake inhibitors, such as venlafaxine (Effexor XR) and duloxetine (Cymbalta)
• mirtazapine (Remeron)

Learn more about Mydayis’s side effects in this article.

What you can do

If you take Mydayis with certain antidepressants, your doctor may prescribe a dosage of Mydayis that’s lower than usual. You should not take a dose of either medication that’s higher than your doctor prescribes.

If you take Mydayis and certain antidepressants together, tell your doctor right away if you have symptoms of serotonin syndrome. These may include:

• restlessness
• sweating
• muscle spasms

Talk with your doctor or pharmacist if you have questions about taking Mydayis with antidepressants.

Interaction with triptans

Mydayis can interact with triptans, which are used to treat migraine episodes.

Mydayis and triptans both can cause serotonin syndrome. This is a serious condition caused by high levels of serotonin in your body. Taking these drugs together can raise your risk of this side effect.

Some triptans that may interact with Mydayis are:

• eletriptan (Relpax)
• rizatriptan (Maxalt)
• sumatriptan (Imitrex)

What you can do

If you take Mydayis and a triptan together, tell your doctor right away if you have symptoms of serotonin syndrome. These may include:

• restlessness
• sweating
• muscle spasms

Talk with your doctor or pharmacist if you have questions about taking Mydayis with triptans.

Interaction with drugs that reduce stomach acid

Mydayis can interact with drugs that reduce stomach acid. These drugs treat indigestion, acid reflux, heartburn, and stomach ulcers. You can buy some of these drugs over the counter without a prescription.

Taking Mydayis with acid-reducing drugs can increase the amount of Mydayis that your body absorbs. This can raise your risk of side effects from Mydayis, such as:

• anxiety
• increased heart rate
• trouble sleeping

Some acid-reducing drugs that may interact with Mydayis are:

• antacids, such as:
  • aluminum hydroxide/magnesium hydroxide (Maalox)
  • calcium carbonate (Tums)
  • calcium carbonate/magnesium hydroxide (Rolaids)
  • aspirin/citric acid/sodium bicarbonate (Alka-Seltzer)
• H2 blockers, such as:
  • cimetidine (Tagamet HB)
  • famotidine (Pepcid AC)
  • ranitidine
• proton pump inhibitors, such as:
  • esomeprazole (Nexium)
  • omeprazole (Prilosec)
  • pantoprazole (Protonix)

What you can do

If you take Mydayis with acid-reducing drugs, your doctor may prescribe a dosage of Mydayis that’s lower than usual. You should not take a dose of either medication that’s higher than your doctor prescribes.

If you take Mydayis and an acid-reducing drug together, tell your doctor right away if you have bothersome side effects from Mydayis.

Talk with your doctor or pharmacist if you have questions about taking Mydayis with acid-reducing drugs.

Are there other interactions with Mydayis?

Mydayis may have other interactions. They could occur with supplements, foods, vaccines, or even lab tests.

Note that the following discussion may not include all other interactions possible with Mydayis.

Does Mydayis interact with supplements?

Before you start taking Mydayis, talk with your doctor and pharmacist about any herbs, vitamins, or supplements you take. Sharing this information with them may help you avoid possible interactions.

Mydayis can interact with tryptophan or 5-HT (serotonin) supplements. Some people take these supplements for anxiety, depression, or sleep problems. Taking Mydayis with these supplements can raise your risk of serotonin syndrome. This is a serious condition caused by high levels of serotonin in your body.

You should talk with your doctor before taking Mydayis with tryptophan or 5-HT.

If you have questions about other interactions that may affect you, talk with your doctor or pharmacist.

Mydayis interactions with herbs

Mydayis can interact with St. John’s wort, which is used to treat depression and other conditions. Taking Mydayis with St. John’s wort can raise your risk of serotonin syndrome. This is a serious condition caused by high levels of serotonin in your body.

You should talk with your doctor before taking Mydayis with St. John’s wort.

Mydayis interactions with vitamins

Mydayis can interact with vitamin C (ascorbic acid). Taking Mydayis with vitamin C can reduce the amount of Mydayis that your body absorbs. It can also increase the amount of Mydayis that your body removes in your urine. Both of these effects can make Mydayis less effective.

It’s important to check with your doctor or pharmacist before taking vitamin products with Mydayis.

Does Mydayis interact with food?

Mydayis can interact with foods and beverages that contain caffeine. Examples include:

• tea
• green tea
• coffee
• cola
• energy drinks
• chocolate

Mydayis and caffeine are stimulants. Consuming caffeine with Mydayis can raise your risk of side effects such as irritability, nervousness, tremor, and trouble sleeping. Your doctor will likely recommend that you avoid consuming large amounts of caffeine while taking Mydayis.

Mydayis can also interact with fruit juices. Taking Mydayis with fruit juices can reduce the amount of Mydayis that your body absorbs. It can also increase the amount of Mydayis that your body removes in your urine. Both of these effects can make Mydayis less effective. Your doctor may recommend that you avoid drinking fruit juices 1 hour before and after taking Mydayis.

If you have questions about consuming other foods or drinks during your treatment with Mydayis, talk with your doctor.

It’s important to note that you can take Mydayis with or without food. But you should always take it in the same way.

Does Mydayis interact with vaccines?

Mydayis currently has no reports of interacting with vaccines. If you have questions about getting certain vaccines during your Mydayis treatment, talk with your doctor.

Does Mydayis interact with lab tests?

Mydayis can increase your cortisol levels, which may affect the results of blood or urine tests that check cortisol levels. These tests may be used to check your adrenal gland function.

If you have questions about having these lab tests during your treatment with Mydayis, talk with the healthcare professional ordering the test.

Does Mydayis interact with cannabis or CBD?

Mydayis currently has no reports of interacting with cannabis (commonly called marijuana) or cannabis products such as cannabidiol (CBD). But as with any drug or supplement, talk with your doctor before using cannabis with Mydayis.

Note: Cannabis is illegal at a federal level but is legal in many states to varying degrees.

Does my health history affect whether I should take Mydayis?

Certain medical conditions or other health factors may raise the risk of interactions with Mydayis. Before starting Mydayis, talk with your doctor about your health history. They’ll determine whether Mydayis is right for you.

Health conditions or other factors that might interact with Mydayis include the following:

Age: Mydayis can cause weight loss and slowed growth in children under age 18 years. Your child’s doctor will monitor your child’s weight and height during long-term treatment with Mydayis.

History of drug or alcohol misuse or dependence: Mydayis has a high risk of misuse and dependence. (Misuse is using the drug in a way that’s not prescribed by a doctor. With dependence, your body needs the drug to feel like it usually does.) Your risk may be higher if you have misused drugs or alcohol in the past. The medication has a boxed warning about this risk, which is described at the start of this article.

Kidney problems: If you have kidney problems, Mydayis can build up in your body. This can raise your risk of side effects from the medication. If you have kidney problems, your doctor may prescribe a dosage of Mydayis that’s lower than usual. But if you have end stage renal (kidney) disease, your doctor likely will not prescribe Mydayis. You can ask them about other treatments that may be better options for you.

High blood pressure: If you have high blood pressure, taking Mydayis could worsen it. Talk with your doctor about whether Mydayis is right for you. If your doctor prescribes Mydayis, your doctor will likely check your blood pressure more often.

Heart conditions: If you have a heart condition, taking Mydayis could make it worse. Talk with your doctor about whether Mydayis is right for you. If you have a serious heart condition, your doctor will likely avoid prescribing Mydayis. The medication may raise your risk of serious problems, including:

• heart attack
• stroke
• sudden death

Blood circulation problems: If you have a blood circulation problem, such as Raynaud phenomenon, Mydayis could make your condition worse. Talk with your doctor about whether this medication is right for you.

Mental health conditions: If you have a mental health condition, taking Mydayis could make your condition worse. These conditions include:

• bipolar disorder
• depression
• schizophrenia

Talk with your doctor about whether Mydayis is right for you.

Tics or Tourette syndrome: If you have a history of tics or Tourette syndrome, taking Mydayis could make your condition worse. Talk with your doctor about whether this medication is right for you.

History of seizure: If you have a history of seizure (for example, due to epilepsy), taking Mydayis could make your seizures worse or more frequent. Talk with your doctor about whether Mydayis is right for you.

Pregnancy: It’s not known whether Mydayis is safe to take during pregnancy. Amphetamines have been reported to cause problems in babies born to people who were dependent on the drugs during pregnancy. (Mydayis contains amphetamines.) These problems include:

• premature delivery
• low birth weight
• withdrawal symptoms

If you’re pregnant or may become pregnant, talk with your doctor before taking Mydayis.

Consider enrolling in the National Pregnancy Registry for Psychiatric Medications if you do take Mydayis during pregnancy. This registry collects details about pregnancy issues reported with Mydayis. To learn more, call 866-961-2388 or talk with your doctor.

Breastfeeding: Mydayis passes into breast milk and may cause side effects in a child who is breastfed. Your doctor will likely recommend that you not breastfeed while taking Mydayis. If you’re breastfeeding or planning to breastfeed, talk with your doctor about your options.

Allergic reaction: If you’ve ever had an allergic reaction to Mydayis, any of its ingredients, or other amphetamines, your doctor likely will not prescribe Mydayis. This is because taking the drug could cause another allergic reaction. You can ask your doctor about other treatments that may be better for you.

How can I prevent interactions?

Taking certain steps can help you avoid interactions with Mydayis. Before starting treatment, talk with your doctor and pharmacist. Things to discuss with them include:

• whether you drink alcohol or use cannabis
• the medications you take, as well as any vitamins, supplements, and herbs
• what to do if you start taking a new drug during your Mydayis treatment

It’s also important to understand Mydayis’s label and other paperwork that may come with the drug. Colored stickers that describe interactions may be on the label. The paperwork, sometimes called the patient package insert or medication guide, may have other details about interactions.

If you did not get paperwork with Mydayis, ask your pharmacist to print a copy for you. If you have difficulty reading or understanding this information, your doctor or pharmacist can help.

Taking Mydayis exactly as prescribed also can help prevent interactions.

Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.