Syfovre (pegcetacoplan) is not known to interact with alcohol, other medications, or supplements. However, receiving the drug while you have certain health conditions may cause harmful effects.

Syfovre is used in adults to treat geographic atrophy from age-related macular degeneration (AMD).

An interaction can occur because one substance causes another substance to have a different effect than expected. Interactions can also occur if you have certain health conditions.

Keep reading to learn about Syfovre’s possible interactions. For a detailed overview of this drug, check out this in-depth Syfovre article.

Syfovre is not known to interact with other drugs. But interactions with other medications could be recognized in the future. For example, new interactions could be reported by people who’ve received Syfovre since it became available.

Before you start receiving Syfovre, tell your doctor and pharmacist about any prescription, over-the-counter, or other drugs you take. Sharing this information with them may help prevent possible interactions.

To learn whether Syfovre interacts with herbs, vitamins, or supplements, see the “Are there other interactions with Syfovre?” section.

If you have questions about drug interactions that may affect you, talk with your doctor or pharmacist.

Certain health conditions or other factors could raise your risk of harm if you receive Syfovre. In such cases, your doctor may not prescribe Syfovre for you. These are known as contraindications. The following list includes contraindications of Syfovre.

If you have an eye infection: If you have an eye infection, your doctor likely won’t prescribe Syfovre for you. This is because receiving the drug could worsen the infection. Your doctor can recommend other treatment options that may be safe to use while you have an eye infection.

If you have eye swelling: If you have swelling in or around your eyes, your doctor likely won’t prescribe Syfovre for you. This is because receiving the drug could worsen the swelling. Talk with your doctor about other treatment options.

If you’ve had an allergic reaction: If you’ve had an allergic reaction to Syfovre or any of its ingredients, your doctor likely won’t prescribe Syfovre for you. This is because receiving the drug could cause another allergic reaction. You can ask your doctor about other treatments that may be better options for you.

Before you start receiving Syfovre, talk with your doctor if any of the factors mentioned here apply to you. Your doctor can determine whether Syfovre is safe for you to receive.

Syfovre is not known to interact with alcohol.

If you have questions about consuming alcohol during Syfovre treatment, talk with your doctor or pharmacist.

Syfovre may have other interactions. They could occur with supplements, foods, vaccines, or even lab tests.

Here are additional interactions that may occur with Syfovre. Note that this is not a full list of all other possible interactions with Syfovre.

Does Syfovre interact with supplements?

Before you start receiving Syfovre, talk with your doctor and pharmacist about any herbs, vitamins, or supplements you take. Sharing this information with them may help you avoid possible interactions.

If you have questions about interactions that may affect you, talk with your doctor or pharmacist.

Syfovre and herbs

There are currently no reports of Syfovre interacting with herbs. But this doesn’t mean that interactions with herbs won’t be recognized in the future.

For this reason, it’s important to check with your doctor or pharmacist before taking any of these products during your Syfovre treatment.

Syfovre and vitamins

There are currently no reports of Syfovre interacting with vitamins. But this doesn’t mean that vitamin interactions won’t be recognized in the future.

For this reason, it’s important to check with your doctor or pharmacist before taking any of these products during your Syfovre treatment.

Does Syfovre interact with food?

There are currently no reports of Syfovre interacting with food. If you have questions about eating certain foods during your treatment with Syfovre, talk with your doctor.

Does Syfovre interact with vaccines or lab tests?

There are currently no reports of Syfovre interacting with vaccines or lab tests. If you have questions about getting certain vaccines or lab tests during your Syfovre treatment, talk with your doctor.

Does Syfovre interact with cannabis or CBD?

There are currently no reports of Syfovre interacting with cannabis (commonly called marijuana) or cannabis products such as cannabidiol (CBD). But as with any drug or supplement, talk with your doctor before using cannabis with Syfovre.

Note: Cannabis is illegal at a federal level but is legal in many states to varying degrees.

Certain medical conditions or other health factors may raise the risk of interactions with Syfovre. Before you receive Syfovre, talk with your doctor about your health history. They’ll determine whether Syfovre is right for you.

Health conditions or other factors that might interact with Syfovre include:

Eye infection: It may not be safe to receive Syfovre while you have an eye infection. To learn more, see the “When should I avoid Syfovre?” section.

Eye swelling: It may not be safe to receive Syfovre if you have swelling in or around your eye. To learn more, see the “When should I avoid Syfovre?” section.

Increased eye pressure: Syfovre may temporarily increase the pressure in your eye after an injection. If you already have a condition that increases pressure in your eye, such as glaucoma, talk with your doctor. They can recommend whether it’s safe to receive Syfovre.

Pregnancy: It’s not known whether Syfovre should be used during pregnancy. If you can become pregnant, your doctor may advise you to use birth control during your Syfovre treatment and for at least 40 days after your final dose. If you’re pregnant or may become pregnant, talk with your doctor before you receive Syfovre.

Breastfeeding: It’s not known whether it’s safe to receive Syfovre while breastfeeding or whether the drug passes into breast milk. If you’re breastfeeding or planning to breastfeed, talk with your doctor about your options.

Allergic reaction: If you’ve had an allergic reaction to Syfovre or any of its ingredients, your doctor will likely not prescribe Syfovre. This is because receiving the drug could cause another allergic reaction. You can ask your doctor about other treatments that may be better for you.

Taking certain steps can help you avoid interactions with Syfovre. Before starting treatment, talk with your doctor and pharmacist. Things to discuss with them include:

  • whether you drink alcohol or use cannabis
  • the list of medications you take, as well as any vitamins, supplements, and herbs
  • what to do if you start taking a new drug during your Syfovre treatment

It’s also important to understand Syfovre’s label and other paperwork that may come with the drug. Colored stickers that describe interactions may be on the label. The paperwork, sometimes called the patient package insert or medication guide, may have other details about interactions.

If you did not get the paperwork with Syfovre, ask your pharmacist to print a copy for you. If you have trouble reading or understanding this information, your doctor or pharmacist can help.

Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.