Valacyclovir is a prescription drug. It comes in the form of a tablet you take by mouth.
Valacyclovir is available as a brand-name drug called Valtrex. It’s also available as a generic drug. Generic drugs usually cost less than the brand-name version. In some cases, they may not be available in every strength or form as the brand-name drug.
This drug may be used as part of a combination therapy. This means you may need to take it with other medications.
Why it’s used
Valacyclovir is used to treat viral infections caused by a group of viruses called herpes simplex viruses. These infections include oral and genital herpes, shingles, and chickenpox.
How it works
Valacyclovir belongs to a class of drugs called antiviral drugs. A class of drugs is a group of medications that work in a similar way. These drugs are often used to treat similar conditions.
The herpes virus spreads in your body by creating more of its cells. Valacyclovir works by making it harder for the herpes virus to multiply (make more cells) in your body.
This drug does not cure herpes infections. The herpes virus may still live in your body after treatment. This means the infection may occur again at a later time even after the symptoms of the first infection are gone. However, this drug can help prevent such a re-infection at a later time.
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Valacyclovir oral tablet doesn’t cause drowsiness, but it can cause other side effects.
More common side effects
The more common side effects of valacyclovir can include:
If these effects are mild, they may go away within a few days or a couple of weeks. If they’re more severe or don’t go away, talk to your doctor or pharmacist.
Serious side effects
Call your doctor right away if you have serious side effects. Call 911 if your symptoms feel life-threatening or if you think you’re having a medical emergency. Serious side effects and their symptoms can include the following:
Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we cannot guarantee that this information includes all possible side effects. This information is not a substitute for medical advice. Always discuss possible side effects with a healthcare provider who knows your medical history.
Reducing your risk of spreading herpesUsing this medication daily may help lower the risk of spreading this disease to your sexual partner. However, you should not have sexual contact with your partner when you have any symptoms of an outbreak of genital herpes. Even if you use safer sex practices such as using a condom, you can still spread genital herpes. Talk with your doctor for more information about how to have safer sex.
An interaction is when a substance changes the way a drug works. This can be harmful or prevent the drug from working well. To help prevent interactions, your doctor should manage all of your medications carefully. Be sure to tell your doctor about all medications, vitamins, or herbs you’re taking.
To find out how valacyclovir oral tablet might interact with something else you’re taking, talk to your doctor or pharmacist.
Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs interact differently in each person, we cannot guarantee that this information includes all possible interactions. This information is not a substitute for medical advice. Always speak with your healthcare provider about possible interactions with all prescription drugs, vitamins, herbs and supplements, and over-the-counter drugs that you’re taking.
This drug comes with several warnings.
Allergy warning
This drug can cause a severe allergic reaction. Symptoms can include:
If you develop these symptoms, call 911 or go to the nearest emergency room.
Don’t take this drug again if you’ve ever had an allergic reaction to it. Taking it again could be fatal (cause death).
Warnings for people with certain health conditions
For people with kidney problems: Your kidneys clear this drug from your body. If you have kidney problems or a history of kidney disease, you may not be able to clear it from your body. This may increase the levels of the drug in your body and cause more side effects. This drug can also make your kidney function worse. To help prevent these problems, your doctor may prescribe a lower dosage of this drug for you.
For people with advanced HIV or a history of transplant: If you have advanced HIV or a history of bone marrow or kidney transplant, you may be at a higher risk of certain blood disorders. These conditions are called thrombocytopenic purpura (TTP) and hemolytic uremic syndrome (HUS). They can result in severely low red blood cells and platelets in your body. TTP or HUS can cause death.
Warnings for other groups
For pregnant women: This drug is a category B pregnancy drug. That means two things:
Talk to your doctor if you’re pregnant or planning to become pregnant. Animal studies do not always predict the way humans would respond. Therefore, this drug should only be used in pregnancy if clearly needed.
Call your doctor right away if you become pregnant while taking this drug.
For women who are breastfeeding: This drug may pass into breast milk and may cause side effects in a child who is breastfed. Talk to your doctor if you breastfeed your child. You may need to decide whether to stop breastfeeding or stop taking this medication.
For seniors: The kidneys of older adults may not work as well as they used to. This can cause your body to process drugs more slowly. As a result, a higher amount of a drug stays in your body for a longer time. This raises your risk of side effects.
For children: This drug has not been studied for use in treatment or prevention of herpes simplex virus (HSV) infection in newborn babies. The following are other age limitations for use of this drug:
All possible dosages and drug forms may not be included here. Your dosage, drug form, and how often you take the drug will depend on:
Drug forms and strengths
Generic: Valacyclovir
Brand: Valtrex
Dosage for oral herpes
Adult dosage (ages 18–64 years)
Child dosage (ages 12–17 years)
Child dosage (ages 0–11 years)
Senior dosage (ages 65 years and older)
The kidneys of older adults may not work as well as they used to. This can cause your body to process drugs more slowly. As a result, a higher amount of a drug stays in your body for a longer time. This raises your risk of side effects.
Your doctor may start you on a lowered dosage or a different treatment schedule. This can help keep levels of this drug from building up too much in your body.
Dosage for genital herpes
Adult dosage (ages 18–64 years)
Child dosage (ages 0–17 years)
This drug has not been studied for the treatment of genital herpes in children younger than 18 years.
Senior dosage (ages 65 years and older)
The kidneys of older adults may not work as well as they used to. This can cause your body to process drugs more slowly. As a result, a higher amount of a drug stays in your body for a longer time. This raises your risk of side effects.
Your doctor may start you on a lowered dosage or a different treatment schedule. This can help keep levels of this drug from building up too much in your body.
Dosage for shingles
Adult dosage (ages 18–64 years)
Child dosage (ages 0–17 years)
This drug has not been studied for the treatment of shingles in children younger than 18 years.
Senior dosage (ages 65 years and older)
The kidneys of older adults may not work as well as they used to. This can cause your body to process drugs more slowly. As a result, a higher amount of a drug stays in your body for a longer time. This raises your risk of side effects.
Your doctor may start you on a lowered dosage or a different treatment schedule. This can help keep levels of this drug from building up too much in your body.
Dosage for chickenpox
Adult dosage (ages 18–64 years)
Child dosage (ages 2–18 years)
Child dosage (ages 0–1 year)
This drug has not been studied or approved for treatment of chickenpox in children younger than two years.
Senior dosage (ages 65 years and older)
The kidneys of older adults may not work as well as they used to. This can cause your body to process drugs more slowly. As a result, a higher amount of a drug stays in your body for a longer time. This raises your risk of side effects.
Your doctor may start you on a lowered dosage or a different treatment schedule. This can help keep levels of this drug from building up too much in your body.
Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we cannot guarantee that this list includes all possible dosages. This information is not a substitute for medical advice. Always speak with your doctor or pharmacist about dosages that are right for you.
Valacyclovir oral tablet is used for short-term treatment of oral herpes, genital herpes, shingles, or chickenpox. It’s used for long-term treatment to prevent genital herpes, and to treat genital herpes that recurs (comes back).
This drug comes with serious risks if you don’t take it as prescribed.
If you stop taking the drug suddenly or don’t take it at all: The symptoms of your viral infection may not get better, or may get worse.
If you miss doses or don’t take the drug on schedule: Your medication may not work as well or may stop working completely. If you’re taking this drug to prevent flare-ups of the infection, a certain amount needs to be in your body at all times. You should not stop taking this drug unless your doctor tells you to stop.
If you take too much: You could have dangerous levels of the drug in your body. Symptoms of an overdose of this drug can include more severe side effects, such as:
If you think you’ve taken too much of this drug, call your doctor or seek guidance from the American Association of Poison Control Centers at 1-800-222-1222 or through their online tool. But if your symptoms are severe, call 911 or go to the nearest emergency room right away.
What to do if you miss a dose: Take your dose as soon as you remember. But if you remember just a few hours before your next scheduled dose, take only one dose. Never try to catch up by taking two doses at once. This could result in dangerous side effects.
How to tell if the drug is working: Your symptoms from the viral infection should improve.
Keep these considerations in mind if your doctor prescribes valacyclovir for you.
General
Storage
Refills
A prescription for this medication is refillable. You should not need a new prescription for this medication to be refilled. Your doctor will write the number of refills authorized on your prescription.
Travel
When traveling with your medication:
Availability
Not every pharmacy stocks this drug. When filling your prescription, be sure to call ahead to make sure your pharmacy carries it.
Hidden costs
You may need to have blood tests during your treatment with this drug. The cost of these tests will depend on your insurance coverage.
Prior authorization
Many insurance companies require a prior authorization for this drug. This means your doctor will need to get approval from your insurance company before your insurance company will pay for the prescription.
There are other drugs available to treat your condition. Some may be better suited for you than others. Talk to your doctor about other drug options that may work for you.
Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up-to-date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or other healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.