Wellbutrin (bupropion) is a prescription drug that’s used in adults to treat major depressive disorder and prevent seasonal affective disorder. Wellbutrin may not be safe to take while pregnant or breastfeeding.

If you can become pregnant, it’s important to consider whether Wellbutrin is a safe option for you.

It’s not known whether Wellbutrin is safe to take during pregnancy. Studies of people taking Wellbutrin SR or Wellbutrin XL in their first trimester of pregnancy didn’t show an increased risk of problems with fetal development (commonly known as birth defects).

Animal studies have shown problems with fetal development in offspring born to animals that were given the drug during pregnancy. However, animal studies don’t always predict what will happen with humans.

If you take Wellbutrin during pregnancy, consider enrolling in the National Pregnancy Registry for Antidepressants. Reporting effects of Wellbutrin during pregnancy helps researchers better understand the drug’s risks when taken during this time.

You can learn more or sign up by calling 844-405-6185 or visiting the registry website.

Depression and pregnancy

Wellbutrin is used to treat major depressive disorder (depression). It’s important to note that untreated depression has many risks during pregnancy, including stillbirth, low birth weight, and preterm birth. To learn more, talk with your doctor.

If you’re currently breastfeeding or planning to do so, it’s important to understand the effects that Wellbutrin could have on you or your child.

Wellbutrin passes into breast milk, but it’s not known whether the drug may cause side effects in a child who is breastfed.

If you’re breastfeeding or considering it, talk with your doctor before taking Wellbutrin. You can discuss the risks and benefits of breastfeeding during your Wellbutrin treatment. If necessary, your doctor can also recommend other healthy ways to feed your child.

Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.