Hepatic hypodensities are areas on the liver that appear darker on imaging tests like CT scans. They mean there is a difference in that area of tissue in the liver. These areas can be caused by a range of conditions, from benign to very serious.

Read on to learn more about hepatic hypodensities, how they appear on CT scans, and what may cause them.

A hepatic hypodensity is an area or spot in the liver that appears darker – less dense – on an imaging scan, typically a non-contrast CT scan. They happen when an area of tissue has more fluid or is a different makeup than the surrounding liver tissue.

Hepatic hypodensities look like dark spots compared to the normal surrounding liver tissue. They may have well-defined borders or appear to have fuzzy or weak edges.

If you have hepatic hypodensities, your doctor will likely order another CT scan with contrast. This means you will be given a dye, either as an injection (shot) or as a liquid by mouth, and then have another CT scan.

The hepatic hypodensities may change, becoming either lighter, darker, or clearer. The way they change will help determine what is causing them.

Many different conditions can cause hepatic hypodensities. These conditions range from harmless to serious. The most common causes include:

Benign conditions

Malignancies (cancer)

Others

  • infection
  • abscess
  • genetic conditions
  • chronic conditions

Hepatic hypodensities are spots on the liver that show up darker on non-contrast CT scans. Because they can be caused by so many different conditions, you will likely need more testing for your doctor to determine what is causing them and what, if any, treatment you need.

You may also need other tests, such as MRI, ultrasound, blood tests, or biopsy, to help your doctor diagnose and treat your condition. Hepatic hypodensities are not always serious, but they can be, so it’s important to attend any additional medical appointments, follow-up testing, and treatment if needed.