Xcopri (cenobamate) is a Schedule V antiseizure prescription tablet indicated for treating partial onset seizures in adults. These focal seizures affect only one brain area rather than causing widespread electrical disturbances. Generally, Medicare drug plans should cover Xcopri or a similar alternative.
Many Medicare Part D or Medicare Advantage Prescription Drug (MAPD) plans should cover Xcopri because these plans must cover most drugs from six protected categories. One of these classes is anticonvulsants, which are drugs that treat seizures.
The out-of-pocket cost of Xcopri without insurance may depend on the dose and the dispensing pharmacy, but generally falls into the range of $1,300.
With Medicare drug plans, the tier system determines how much you may actually pay for medications. Higher tier drugs may have a higher copayment, while generics typically land in lower, more affordable tiers.
No generic version of Xcopri is available, but starting in 2025, Medicare caps annual prescription costs at $2,000 and covers all medication expenses beyond this threshold. This cap may rise slightly to $2,100 in 2026.
Your Medicare drug plan may include a deductible and a monthly premium, which vary across plans. However, no Medicare drug plan can charge a deductible higher than $590 in 2025.
Optum Perks is owned by RVO Health. By clicking on this link, we may receive a commission. Learn more.
The manufacturer of Xcopri currently offers a trial program through which you can receive a 1-month supply of the drug at no cost. If your doctor prescribes this drug, you can try it out for 1 month through this program without using your Medicare coverage.
Consider exploring online resources, such as the Medicine Assistance Tool and NeedyMeds, that may offer additional guidance on lowering drug costs.